In humans, there is a very complex valve system that regulates the passage between the esophagus and the stomach. In this way, the escape of the food in the stomach, especially acid and bile, into the esophagus is prevented. The most important cause of reflux is the insufficiency of this valve system or the slipping of the valve system, known as stomach hernia among the people, from the abdominal cavity to the chest cavity, resulting in inadequate functioning of the valve. In reflux disease, there is no high stomach acidity. Stomach contents escaping into the esophagus, even at normal or even low acid levels, cause damage to the esophagus. It is not necessary to have valve insufficiency for reflux to occur. Reflux may also occur in diseases of the esophagus and in case of gastric emptying disorder.
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